
Position Title
Professor
Position Title
Professor
- Biochemistry and Molecular Medicine
Bio
Education:
- Ph.D 1998, Nankai University
- B.S. 1993, Central China Normal University
Department: Biochemistry and Molecular Medicine
Research Interests:
Clinical Pharmacology and Toxicology, Metabolic Fate and Pharmacokinetics
Research Summary:
Dr. Yu’s research interests include noncoding microRNA pharmacoepigenetics and cancer therapy. The ultimate goal of his research is to translate noncoding RNAs to new therapeutics. Current efforts in his laboratory are directed to the investigation of (a) the mechanistic actions of microRNAs in the regulation of cancer cellular processes including drug/xenobiotic disposition and tumor progression, (b) novel RNA bioengineering technology, and (C) recombinant RNAs for research and therapy. Dr. Yu also directs the PK/PD Bioanalytical Core Facility that provides services in support of the clinical and preclinical drug development programs, and the Molecular Pharmacology Shared Resources that supports high-quality collection, processing and analysis of clinical specimens and conducts preclinical modeling and evaluation of novel anticancer agents or combination.
Highlighted Techniques:
Bioanalysis using LC-MS/MS and HPLC; RNA purification using FPLC; Molecular and cellular biology techniques; Animal models
Courses/Teaching:
- PTX201 Principles of Pharmacology and Toxicology
- VMB253 Drug and Toxicant Metabolism
Lab Rotation Availability: Yes
Funding Sources: NIH
PubMed listing