Angela Haczku, MD, Ph.D.

Angela Haczku

Position Title
Professor

  • Internal Medicine - Pulmonary
Bio

Education:

  • M.D.: University Medical School of Debrecen, Hungary 
  • Ph.D.: Immunology, Imperial College, London UK
  • Internship: Internal Medicine, University Medical School of Debrecen, Hungary
  • Residency: Internal and Pulmonary Medicine, University Medical School of Debrecen, Hungary
  • Postdoctoral Fellowship: Allergy and Clinical Immunology, National Jewish Medical and Research Center, Denver, CO


Research Interests:

Respiratory immunology, pathogenesis of allergy, asthma, COPD and pulmonary infections. In vivo (animal) and in vitro models of disease mechanisms. Effects of environmental exposures such as air pollution, allergens, cigarette smoke and psychosocial stress on airway inflammation.


Research Summary:

Dr. Haczku's laboratory studies the effects of environmental exposures (allergen, ozone, cigarette smoke, psychosocial stress and infections) with a focus on how the innate and adaptive immune systems cooperate during development and resolution of airway inflammation. We use lung physiology and pathology to demonstrate the role of lung collectins, IgE-mediated immune mechanisms and psychosocial stress in airway and parenchymal pathologies. We have an in vitro ozone exposure system using human airway epithelial cells (both submerged and ALI) and study the expression of IL-33 and TSLP in response ozone. We also investigate the role of innate lymphoid cells (ILC2) in mice, rhesus macaques and in asthma patients in airway inflammation. 


Lab Rotation Availability: Yes
PubMed listing