Education:

• Mayo Clinic, Rochester, Minnesota, Postdoc 2006
• University of Kansas Medical Center, Ph.D. 2000
• Pittsburg State University, B.S. 1993

Department: Biochemistry and Molecular Medicine
Research Interests:

Genetic and Developmental Pharmacology/Toxicology, Clinical Pharmacology/Toxicology

Research Summary:

Molecular mechanisms of resistance to chemotherapy; Experimental therapeutics targeting homologous recombination pathway and synthetic lethality with PARP inhibitors; Experimental therapeutics targeting protein homeostasis and synergistic combinations with modulators of unfolded protein response and autophagy; PROteolysis-TArgeting Chimeria (PROTAC)-based drug development; Development of novel therapeutics in tissue-specific synthetic lethality; Immunogenic cell death and molecular mechanisms to enhance immunotherapy.

Highlighted Techniques:

NA

Courses/Teaching:

• NA

Lab Members:

NA

Lab Rotation Availability: Yes
Funding Sources: Department of Defense Ovaraian Cancer Research Program, American Cancer Society, National Institutes of Health, Ovarian Cancer Research Fund
PubMed listing