Education:

• University of Massachusetts, Boston, MA. B.S.
• Boston University, Boston, MA. Ph.D.
• Lawrence Livermore National Laboratory, Livermore, CA. Postdoc

Department: Radiation Oncology
Research Interests:

Environmental Toxicology, Molecular, Cellular, and Biochemical Toxicology

Research Summary:

Dr. Matthew Coleman is currently an adjunct professor at the University of California at Davis in the department of radiation oncology and a member of the NIH Cancer Center within the medical center. Dr. Coleman also holds a scientific appointment at the Lawrence Livermore National Laboratory in Livermore, California. Dr. Coleman's research focuses on understanding the processes involved in genome instability following genotoxic stresses such as ionizing radiation, with the hope of developing novel targets for potential therapy. Dr. Coleman's research uses novel approaches in nanotechnology to help characterize biological components involved in cell signaling. He has worked with scientist (Sebastan W. and Thomas H.) at CBST for the last 6 years on the development of biomarkers of disease as well as instrumentation for biological detection and characterization. Dr. Coleman's technical training is in molecular biology where he received his B.A. from the University of Massachusetts in 1987, and his Ph.D. in biophysical studies of proteins from Boston University in 1997. He has authored over 60 publications in peer-reviewed journals, published proceedings and book chapters covering a diverse breadth of molecular biology and biochemistry. Dr. Coleman has three patents and 6 patents pending related to biomarker discovery and biotechnology. For his work in the area of nanolipoproteins -membrane protein complexes Dr. Coleman received a Nanotechnology 50 award for development of his innovative approach to produce and solubilize membrane proteins using nanoparticles.

Highlighted Techniques:

Approaches in nanotechnology

Courses/Teaching:

• RON 420 Radiobiology Lecture Course
• RON 199 Research in Radiation Biology

Lab Members:

Wei He, PTX Graduate Student, Ehson Ghandehari, BME Graduate Student

Lab Rotation Availability: Yes
Funding Sources: NIH, DOE, LLNL
PubMed listing